Patient guide

What to expect at your first infusion appointment

Your first infusion visit should feel more understandable than overwhelming. Here is what most patients can expect before arrival, during the appointment, and after they head home.

Medically reviewed by the physicians of Sunshine Rheumatology and Arthritis Center. Last updated March 2026.

Infusion treatment chair in the clinic

Before you arrive

  • Eat a light meal and drink water unless your care team gives different instructions
  • Wear comfortable clothing with easy access to your arm
  • Bring your insurance information, current medication list, and something to help pass the time
  • Complete any lab work or authorization steps your provider asked for ahead of time
  • Ask whether you should drive yourself or arrange a ride after the visit

Questions worth asking ahead of time

  • How long should I expect to be in the office?
  • Do I need to stop or adjust any medications before treatment day?
  • Will I receive pre-medications before the infusion starts?
  • What symptoms should I report during the visit?
  • When will my next infusion likely be scheduled?

If you are still deciding whether infusion therapy makes sense for your condition, start with our general infusion therapy guide.

Visit day

What usually happens during the appointment

The exact steps depend on the medication, but most first visits follow a similar rhythm so the care team can keep you comfortable and monitor your response.

1. Check-in and review

Your nurse reviews the medication plan, confirms any recent symptoms or infections, and checks that the right treatment and dose are ready.

2. IV placement

The IV start usually feels like a brief pinch. Once the line is in place, most patients settle in comfortably.

3. Monitoring during treatment

Vital signs and symptoms are monitored throughout the visit. If you feel flushed, itchy, dizzy, or just “off,” tell the nurse right away.

4. Wrap-up and next steps

Before you leave, the team reviews how you felt, when to call the office, and what follow-up or next infusion date to expect.

Practical planning tips

Can I eat before my infusion?

Most patients can and should eat a light meal beforehand. It often helps you feel more comfortable during a longer appointment.

How long will I be there?

Some medications take less than an hour, while others take several hours. First visits can run longer because the team monitors your initial response carefully.

What if I feel nervous?

That is common. Bring a book, headphones, tablet, or another comfort item. Let the nursing team know you are anxious so they can explain each step as the appointment moves along.

What if I have a reaction?

Infusion reactions are uncommon, but the team is trained to recognize and manage them quickly. Report any new symptom as soon as you notice it.

After your first infusion

Many patients are able to go back to their normal routine the same day, although some feel tired and prefer a lighter schedule after treatment. If your provider wants you to watch for any symptoms at home, the team will review those instructions before you leave.

Insurance follow-up, lab timing, and future scheduling can vary by medication. Our insurance page covers the basics, and your provider team can explain what applies to your specific treatment plan.

Infusion therapy is available at all five of our offices. Visit any location page for providers, hours, and office-specific details.

Need more detail?

Have more questions about infusion therapy?

Learn how infusion treatment works across our offices on the infusion clinic page, explore condition and medication guides in our educational resources, or review the ACR medication guides for national reference information.

Text/Call 813-333-5080 New Patient